FITC标记的磷酸核糖胺咪唑羧化酶抗体
产品名称: FITC标记的磷酸核糖胺咪唑羧化酶抗体
英文名称: Anti-PAICS/FITC
产品编号: HZ-6369R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-PAICS/FITC Conjugated antibody
FITC标记的磷酸核糖胺咪唑羧化酶抗体
英文名称 | Anti-PAICS/FITC |
中文名称 | FITC标记的磷酸核糖胺咪唑羧化酶抗体 |
别 名 | ADE2; ADE2H1; AIR carboxylase; AIRC; DKFZp781N1372; MGC1343; MGC5024; Paics; PAIS; Phosphoribosylaminoimidazole carboxylase; PUR6_HUMAN; SAICAR synthetase. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 染色质和核信号 信号转导 激酶和磷酸酶 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 47kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PAICS |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Subunit: Homooctamer. Similarity: In the N-terminal section; belongs to the SAICAR synthetase family. In the C-terminal section; belongs to the AIR carboxylase family. Database links: Entrez Gene: 10606 Human Entrez Gene: 67054 Mouse Entrez Gene: 140946 Rat Omim: 172439 Human SwissProt: P22234 Human SwissProt: Q9DCL9 Mouse SwissProt: P51583 Rat Unigene: 518774 Human Unigene: 709570 Human Unigene: 182931 Mouse Unigene: 431705 Mouse Unigene: 3015 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码在其N-末端区域中含有磷酸核糖氨基酰咪唑羧化酶活性的双功能酶和其C-末端区域中的磷酸核糖氨基酰咪唑琥珀卡多酰胺合成酶。它催化嘌呤生物合成的步骤6和7。该基因与一个在同一途径中编码酶的位点紧密连锁和分散化转录,并对两个基因的转录进行协调调节。人类基因组含有几个基因的假基因。该基因已发现编码不同亚型的多个转录变体。[ RefSeq,JUL 2008 ]提供。