Anti-CDKN1B Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001665P-50ul	solarbio	50ul	960.00元
K001665P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-CDKN1B Polyclonal Antibody
别名	CDKN4;KIP1;MEN1B;MEN4;P27KIP1
应用	WB IHC IF
稀释比例	WB 1:500-2000. IHC 1:50-200. IF 1:20-50.
交叉反应	Human Mouse Rat
蛋白分子量	22kDa
Gene ID	1027
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human CDKN1B
性状	液体
Public Immunogen Range	Recombinant protein of human CDKN1B
Subcellular Locations	Cytoplasm Endosome Nucleus
Swiss Prot	P46527
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).