PSME2 monoclonal antibody (M02), clone 1G4
产品名称： PSME2 monoclonal antibody (M02), clone 1G4
英文名称： PSME2 monoclonal antibody (M02), clone 1G4
产品编号： H00005721-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PSME2.
- Immunogen:
- PSME2 (NP_002809, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MAKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEMETDKQEKKEVHK
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- PSME2 monoclonal antibody (M02), clone 1G4 Western Blot analysis of PSME2 expression in MCF-7 ( Cat # L046V1 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of PSME2 expression in transfected 293T cell line by PSME2 monoclonal antibody (M02), clone 1G4.
Lane 1: PSME2 transfected lysate(27.4 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to PSME2 on formalin-fixed paraffin-embedded human stomach carcinoma. [antibody concentration 6 ug/ml]
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of PSME2 transfected lysate using anti-PSME2 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PSME2 MaxPab rabbit polyclonal antibody.
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PSME2 is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5721
- GeneBank Accession#:
- NM_002818
- Protein Accession#:
- NP_002809
- Gene Name:
- PSME2
- Gene Alias:
- PA28B,PA28beta,REGbeta
- Gene Description:
- proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
- Omim ID:
- 602161
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. [provided by RefSeq
- Other Designations:
- 11S regulator complex beta subunit,MCP activator, 31-kD subunit,activator of multicatalytic protease subunit 2,cell migration-inducing protein 22,proteasome activator 28-beta,proteasome activator hPA28 subunit beta,proteasome activator subunit 2
- Gene Pathway
- Related Disease