SPPL2A抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
SPPL2A抗体

SPPL2A抗体

商家询价

产品名称: SPPL2A抗体

英文名称: SPPL2AAntibody

产品编号: XY13255-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 SPPL2A抗体Applications

In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 13255-1-AP;human colon tissuehuman colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP(SPPL2A antibody) at dilution of 1:500
  • 13255-1-AP;human testisImmunohistochemical of paraffin-embedded human testis using 13255-1-AP(SPPL2A antibody) at dilution of 1:50 (under 10x lens)
  • 13255-1-AP;human testisImmunohistochemical of paraffin-embedded human testis using 13255-1-AP(SPPL2A antibody) at dilution of 1:50 (under 40x lens)
Positive WB detected in Human colon tissue, Jurkat cells, mouse colon tissue
Positive IHC detected in Human testis tissue, human kidney tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
I SPPL2A抗体P = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information SPPL2A抗体
Immunogen SPPL2A fusion protein ag3935 Full name Signal peptide peptidase-like 2A
Calculated molecular
weight
520aa,58 kDa Observed molecular 
weight
58kd
GenBank accession 
number
BC025740 Gene ID (NCBI) 84888
Gene symbol SPPL2A Synonyms IMP 3, IMP3, Intramembrane protease 3, Presenilin like protein 2, PSL2, SPP like 2A, SPPL2A
Background

SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273). This protein has a signal peptide with 25 amino acid and seven glycosylation sites. SPPL2A抗体

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