RUNX1 polyclonal antibody
产品名称: RUNX1 polyclonal antibody
英文名称: RUNX1 polyclonal antibody
产品编号: PAB0189
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RUNX1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 231-245 of human RUNX1.
- Sequence:
- AFNPQPQSQMQDTRQ
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Physiogenomic resources for rat models of heart, lung and blood disorders.
Malek RL, Wang HY, Kwitek AE, Greene AS, Bhagabati N, Borchardt G, Cahill L, Currier T, Frank B, Fu X, Hasinoff M, Howe E, Letwin N, Luu TV, Saeed A, Sajadi H, Salzberg SL, Sultana R, Thiagarajan M, Tsai J, Veratti K, White J, Quackenbush J, Jacob HJ, Lee NH.Nat Genet. 2006 Feb;38(2):234-9. Epub 2006 Jan 15.
- 2.
- Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI.Leuk Res. 2005 Jul;29(7):813-20.
- Entrez GeneID:
- 861
- Gene Name:
- RUNX1
- Gene Alias:
- AML1,AML1-EVI-1,AMLCR1,CBFA2,EVI-1,PEBP2aB
- Gene Description:
- runt-related transcription factor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- AML1-EVI-1 fusion protein,acute myeloid leukemia 1,aml1 oncogene,core-binding factor, runt domain, alpha subunit 2
- Related Disease
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Blast Crisis
- Cardiovascular Diseases
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Immune System Diseases
- Leukemia, chronic myeloid
- Leukemia, Myelocytic, Acute
- Leukemia, Myeloid, Acute