CUL2 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CUL2 抗体

CUL2 抗体

商家询价

产品名称： CUL2 抗体

英文名称： CUL2 Antibody

产品编号： XY10981-2

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CUL2 抗体

Applications
In-house applications ELISA, WB, IHC, IF, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 2 citations –view here
Species specificity Human; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 10981-2-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 10981-2-AP(CUL2 antibody) at dilution of 1:100
  • 10981-2-AP;HeLa cellsIP Result of anti-CUL2 (IP:10981-2-AP, 4ug; Detection:10981-2-AP 1:200) with HeLa cells lysate 2500ug.
  • 10981-2-AP;human prostate cancerImmunohistochemical of paraffin-embedded human prostate cancer using 10981-2-AP(CUL2 antibody) at dilution of 1:50 (under 40x lens)
  • 10981-2-AP;HepG2Immunofluorescent analysis of HepG2 cells, using CUL2 antibody 10981-2-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Positive WB detected in HeLa cells
Positive IP detected in HeLa cells
Positive IHC detected in Human prostate cancer tissue, human kidney tissue, human testis tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100
CUL2 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CUL2 fusion protein ag1434 Full name Cullin 2
Calculated molecular
weight		 87 kDa Observed molecular 
weight		 87 kDa
GenBank accession 
number		 BC009591 Gene ID (NCBI) 8453
Gene symbol CUL2 Synonyms CUL 2, CUL2, cullin 2
BackgroundCUL2 抗体

The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases, participating in the proteolysis through the ubiquitin-proteasome pathway. Humans express seven cullin proeins: CUL1–3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.CUL2 抗体

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