ERN1 polyclonal antibody
产品名称： ERN1 polyclonal antibody
英文名称： ERN1 polyclonal antibody
产品编号： PAB12433
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ERN1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 700-800 of human ERN1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response.
Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W.J Biol Chem. 2008 May 2;283(18):11905-12. Epub 2008 Feb 15.
- 2.
- Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.
Lipson KL, Fonseca SG, Ishigaki S, Nguyen LX, Foss E, Bortell R, Rossini AA, Urano F.Cell Metab. 2006 Sep;4(3):245-54.
- 3.
- WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells.
Fonseca SG, Fukuma M, Lipson KL, Nguyen LX, Allen JR, Oka Y, Urano F.J Biol Chem. 2005 Nov 25;280(47):39609-15. Epub 2005 Sep 29.
- Entrez GeneID:
- 2081
- Protein Accession#:
- O75460
- Gene Name:
- ERN1
- Gene Alias:
- FLJ30999,IRE1,IRE1P,MGC163277,MGC163279
- Gene Description:
- endoplasmic reticulum to nucleus signaling 1
- Omim ID:
- 604033
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq
- Other Designations:
- ER to nucleus signalling 1,endoplasmic reticulum to nucleus signalling 1,inositol-requiring 1,protein kinase/endoribonuclease
- Interactome
- Gene Pathway