LAMA4 purified MaxPab mouse polyclonal antibody (B02P)
产品名称： LAMA4 purified MaxPab mouse polyclonal antibody (B02P)
英文名称： LAMA4 purified MaxPab mouse polyclonal antibody (B02P)
产品编号： H00003910-B02P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human LAMA4 protein.
- Immunogen:
- LAMA4 (AAH04241.1, 1 a.a. ~ 120 a.a) full-length human protein.
- Sequence:
- MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEVQCPCHCHPAGAPAPPRAVPHSSFSLSPPLSSPQCLESFTWARSVRKLEIKSFPL
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of LAMA4 expression in transfected 293T cell line (H00003910-T02) by LAMA4 MaxPab polyclonal antibody.
Lane 1: LAMA4 transfected lysate(13.2 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3910
- GeneBank Accession#:
- BC004241.1
- Protein Accession#:
- AAH04241.1
- Gene Name:
- LAMA4
- Gene Alias:
- DKFZp686D23145,LAMA3,LAMA4*-1
- Gene Description:
- laminin, alpha 4
- Omim ID:
- 600133
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017039,OTTHUMP00000017043,laminin alpha 4 chain