MVK polyclonal antibody
产品名称： MVK polyclonal antibody
英文名称： MVK polyclonal antibody
产品编号： PAB24918
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MVK.
- Immunogen:
- A synthetic peptide corresponding to MVK.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 42
- Reactivity:
- Human
- Specificity:
- MVK polyclonal antibody detects endogenous levels of MVK protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of COS-7 cell lysate with MVK polyclonal antibody (Cat # PAB24918).
- Entrez GeneID:
- 4598
- Gene Name:
- MVK
- Gene Alias:
- FLJ96772,LRBP,MK,MVLK
- Gene Description:
- mevalonate kinase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- LH receptor mRNA-binding protein,mevalonic aciduria
- Related Disease
- Amyloidosis
- Autoimmune Diseases
- Behcet Syndrome
- Coronary Artery Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Diarrhea
- Dyslipidemias
- Familial Mediterranean Fever
- Familial Mediterranean fever
- Genetic Predisposition to Disease
- Hyperlipidemias
- Hypertriglyceridemia
- Inflammation
- Irritable Bowel Syndrome
- Narcolepsy
- Pain
- Stomatitis, Aphthous
- Syndrome