FITC标记的神经内分泌肽QRFP抗体
产品名称： FITC标记的神经内分泌肽QRFP抗体
英文名称： Anti-QRFP/FITC
产品编号： HZ-11534R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-QRFP/FITC Conjugated antibody
FITC标记的神经内分泌肽QRFP抗体
| 产品编号 | bs-11534R-FITC |
| 英文名称 | Anti-QRFP/FITC |
| 中文名称 | FITC标记的神经内分泌肽QRFP抗体 |
| 别 名 | 26RFa; Neuropeptide RF-amide; OX26_HUMAN; pyroglutamylated RFamide peptide; P518; Pyroglutamylated arginine-phenylalanine-amide peptide; QRF-amide; Qrfp. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 5kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human QRFP (91-133aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: QRFP is a 136 amino acid secreted protein that is widely expressed in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis and thyroid, QRFP is a member of the RFamide neuropeptide family. QRFP may be involved in aldosterone secretion by the adrenal gland and is also implicated in stimulating metabolic rate, locomotor activity and increasing blood pressure. Considered a ligand for the G-protein coupled receptor GPR103, QRFP may have orexigenic activity, thereby acting as an appetite stimulant. The gene encoding QFRP is located on human chromosome 9, which consists of about 145 million bases, comprises roughly 4% of the human genome and encodes nearly 900 genes. Function: Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland. Subunit: Ligand for the G-protein coupled receptor QRFPR/GPR103 Subcellular Location: Secreted. Tissue Specificity: Expressed widely in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus, and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis, and thyroid. Similarity: Belongs to the RFamide neuropeptide family. Database links: Entrez Gene: 347148 Human Omim: 609795 Human SwissProt: P83859 Human Unigene: 660704 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
QFRP是一种136氨基酸分泌蛋白，广泛表达于小脑、髓质、垂体、视网膜、前庭核和白质中的表达水平最高的脑中。在膀胱、结肠、冠状动脉、甲状旁腺、前列腺、睾丸和甲状腺中也有表达，QrFP是rFAMIDE神经肽家族的成员。QFRP可能参与肾上腺醛固酮分泌，也与刺激代谢率、运动活性和增加血压有关。考虑到G-蛋白偶联受体GPR103的配体，QrFP可能具有促食欲活性，从而作为食欲兴奋剂。编码QFRP的基因位于人类9号染色体上，由约1亿4500万个碱基组成，约占人类基因组的4%，编码近900个基因。