抗人CD38鼠单抗-抗体-抗体-生物在线
北京义翘神州科技有限公司
抗人CD38鼠单抗

抗人CD38鼠单抗

商家询价

产品名称： 抗人CD38鼠单抗

英文名称： CD38 T10 CD38

产品编号： 10818-MM04

产品价格： null

产品产地： 北京

品牌商标： 义翘神州(SinoBiologi

更新时间： null

使用范围： western blot

北京义翘神州科技有限公司
  • 联系人 :
  • 地址 : 北京亦庄东区科创十街18号院9号楼306室
  • 邮编 : 100176
  • 所在区域 : 北京
  • 电话 : 点击查看
  • 传真 : 点击查看
  • 邮箱 : marketing@sinobiological.cn
进入展台 

官方网址：http://www.sinobiological.cn/CD38-Antibody-g-2107.html
ADP-ribosyl cyclase 1 ( CD38 ) Antibody Datasheet
 
 
 
CD38抗体产品信息
 
  
 免疫原 :   
Recombinant human CD38 protein (  Catalog#10818-H08H  )
 		 
 
  
克隆号 :
 		  
1H5C11E12
 		 
 
 Ig Type :  
Mouse  IgG1
 		 
 
 缓冲液 : 0.2 μm filtered solution in PBS with 5% trehalose 
 
 制备方法 :   
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, human cell-derived, recombinant human CD38 ( rhCD38; Catalog#10818-H08H; NP_001766.2; Val 43 - Ile 300). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
 		 
  
 
CD38抗体使用指南
 
  
  
特异性 : 
 		  
Human CD38
 		 
 
    
No cross-reactivity with human cell lysate ( 293 cell line ) in WB and ELISA.
 		 
 
 Western blot : This antibody can be used at 1-2ug/mL with the appropriate secondary reagents to detect CD38 in WB. Using a DAB detection system, the detection limit for CD38 is approximately 6.25ng/lane under non-reducing conditions and 2ng/lane under reducing conditions. 
 
 储存方法 : This antibody can be stored at 2℃-8℃ for 1 month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
 Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.		 
  
 
CD38 Antibody Related Products & Topics
 
 
相关研究领域:
 
Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hematopoietic Stem Cell Marker>>CD38
 
Cancer>>Cancer Stem Cell (CSC)>>CD38
 
Cancer>>Cancer Biomarkers>>CD38
 
Immunology>>Adaptive Immunity>>T Cell>>Regulatory T Cell>>CD38
 
Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD38
 
Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>>CD38
 
Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Regulatory T Cells>>CD38
 
蛋白:
 
  
 Molecule Species Description //For Detailed Info.------CLICK! Cat No 
 
 CD38 Human CD38 Protein, Recombinant 10818-H08H 
 
 CD38 Mouse CD38 Protein, Recombinant 50191-M08H 
  
 
抗体:
 
  
 Molecule Application Description //For Detailed Info.------CLICK! Cat No 
 
 Human 
 CD38		 ELISA Mouse Monoclonal Antibody 10818-MM03 
 
 Human 
 CD38		 WB Mouse Monoclonal Antibody 10818-MM04 
 
 Human 
 CD38		 WB, ELISA Rabbit Monoclonal Antibody 10818-R011 
 
 Human 
 CD38		 WB, ELISA Rabbit Polyclonal Antibody 10818-RP01 
 
 Human 
 CD38		 WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10818-RP02 
 
 Mouse 
 CD38		 WB, ELISA Rabbit Monoclonal Antibody 50191-R032 
 
 Mouse 
 CD38		 WB, ELISA Rabbit Polyclonal Antibody 50191-RP01 
 
 Mouse 
 CD38		 WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 50191-RP02 
  
 
 
CD38 Antibody Background
 
 
CD38, also known as ADP-ribosyl cyclase, is a glycoprotein expressed on the surface of immune cells including B and T lymphocytes, osteoclasts, as well as cardiac, pancreatic, liver and kidney cells. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic β cells. CD38 functions in cell adhesion, signal transduction and calcium signaling. Defects of CD38 is associated with impaired immune responses, metabolic disturbances, and behavioral modifications, and thus has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.
 
 
参考文献
 
 
     
  1. Jackson, D.G. et al., 1990, J. Immunol. 144 (7): 2811-2815.
    2.  
  2. Kato, I. et al.,1995, J. Biol. Chem. 270: 30045-30050.
    3.  
  3. Sun, L. et al., 1999, J. Cell Biol. 146:1161-1171.
    4.  
  4. Partida-Sanchez, S. et al., 2001, Nature Med. 7: 1209-1216.
    5.  
  5. Schuber, F. et al., 2004, Curr. Mol. Med. 4: 249-261.
    6.  
  6. Orciani, M. et al., 2008, J. Cell. Biochem. 105 (3): 905-912.
    7.