FITC标记的β半乳糖苷酶1样蛋白3抗体
产品名称: FITC标记的β半乳糖苷酶1样蛋白3抗体
英文名称: Anti-GLB1L3/FITC
产品编号: HZ-8409R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-GLB1L3/FITC Conjugated antibody
FITC标记的β半乳糖苷酶1样蛋白3抗体
产品编号bs-8409R-FITC英文名称Anti-GLB1L3/FITC中文名称FITC标记的β半乳糖苷酶1样蛋白3抗体别 名Beta galactosidase 1 like protein 3; Beta-galactosidase-1-like protein 3; FLJ90231; Galactosidase, beta 1 like 3; GLB1L 3; Glb1l3; GLBL3_HUMAN; LOC112937; OTTHUMP00000235427. 规格价格100ul/2980元 购买 大包装/询价说 明 书100ul 研究领域细胞生物 免疫学 抗体来源Rabbit克隆类型Polyclonal交叉反应Human, Mouse, Rat, Chicken, Horse, 产品应用IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.分 子 量75kDa性 状Lyophilized or Liquid浓 度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human GLB1L3亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.产品介绍background: GLB1L3 is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. Similarity: Belongs to the glycosyl hydrolase 35 family. Database links: UniProtKB/Swiss-Prot: Q8NCI6.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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GLB1L3是属于糖基水解酶35家族的653氨基酸。GLB1L3作为三个交替剪接的亚型存在,并被编码到人类染色体11q25的基因编码。大约有1亿3500万个碱基对和1400个基因,染色体11构成了人类基因组DNA的4%,被认为是一个基因和疾病相关的密集染色体。11号染色体编码ATM基因是调控双链DNA断裂后细胞周期阻滞和凋亡的重要因素。ATM突变导致称为共济失调毛细血管扩张症。Jurvl和Lange Nielsen综合征、杰克布森综合征、尼曼匹克病、遗传性血管水肿和Smith-LeMi-Opz综合征也与11号染色体上的缺陷有关。