FOXC2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
FOXC2抗体

FOXC2抗体

商家询价

产品名称： FOXC2抗体

英文名称： FOXC2Antibody

产品编号： XY23066-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 FOXC2抗体

Applications
Tested Applications: ELISA, WB
Cited applications WB
Specificity Reaction: Human, Rat, Mouse; Other species are not tested.Please decide the specificity by homology
Positive WB detected in A375 cells, A431 cells, rat spleen tissue
Recommended dilution WB : 1:500-1:5000
 FOXC2抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 23066-1-AP;A375 cellsA375 cells were subjected to SDS PAGE followed by western blot with 23066-1-AP(FOXC2 antibody) at dilution of 1:1000
Product Information FOXC2抗体
Source: Rabbit Purify: Antigen Affinity purified
IsoType: IgG Storage: PBS with 0.0.2% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: FOXC2 fusion protein ag19378 Full Name: Forkhead box C2 (MFH-1, mesenchyme forkhead 1)
Caculated Molecular
Weight:		 501aa,54 kDa Observed Molecular 
Weight:		 56 kDa
GenbankNo BC113437 GeneID: 2303
Symbol FOXC2 Synonyms FKHL14, Forkhead box protein C2, FOXC2, LD, Mesenchyme fork head protein 1, MFH 1, MFH 1 protein, MFH1, Transcription factor FKH 14
Background FOXC2抗体

Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.Defects in FOXC2 are the cause of lymphedema hereditary type 2 (LMPH2) [MIM:153200]; also known as Meige lymphedema. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections, and physical impairment. Defects in FOXC2 are a cause of lymphedema-yellow nails (LYYN) [MIM:153300]. LYYN is characterized by yellow, dystrophic, thick and slowly growing nails, associated with lymphedema and respiratory involvement. Lymphedema occurs more often in the lower limbs. It can appear at birth or later in life. Onset generally follows the onset of ungual abnormalities. Defects in FOXC2 are a cause of lymphedema-distichiasis (LYD) [MIM:153400]. LYD is characterized by primary limb lymphedema usually starting at puberty (but in some cases later or at birth) and associated with distichiasis (double rows of eyelashes, with extra eyelashes growing from the Meibomian gland orifices).This antibody specifically recognizes the 56 kDa FOXC2 protein. FOXC2抗体

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