FITC标记的FBXO22蛋白抗体
产品名称： FITC标记的FBXO22蛋白抗体
英文名称： Anti-FBXO22/FITC
产品编号： HZ-16047R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-FBXO22/FITC Conjugated antibody
FITC标记的FBXO22蛋白抗体
| 英文名称 | Anti-FBXO22/FITC |
| 中文名称 | FITC标记的FBXO22蛋白抗体 |
| 别 名 | 0610033L19Rik; 1600016C16Rik; F box only protein 22; F box protein 22; F box protein FBX22p44; F-box only protein 22; F-box protein FBX22p44; FBX22; FBX22_HUMAN; FBXO 22; FBXO22; FIST domain containing 1; FISTC1; FLJ13986; MGC124731; MGC31799. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 转录调节因子 表观遗传学 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 44kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FBXO22 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Tissue Specificity: Predominantly expressed in liver. Similarity: Contains 1 F-box domain. Database links: Entrez Gene: 26263 Human Entrez Gene: 71999 Mouse Entrez Gene: 300724 Rat Omim: 609096 Human SwissProt: Q8NEZ5 Human SwissProt: Q78JE5 Mouse Unigene: 591115 Human Unigene: 276429 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的F盒蛋白家族的成员，其特征在于约40个氨基酸基序，F盒。F-box蛋白是一类的泛素蛋白连接酶复合称为SCFs的四个亚基的功能（SKP1的cullin-F-box），磷酸化依赖的泛素化。F-box蛋白分为三类：含有WD-40域FBWs，含有富亮氨酸重复用机器，和含有不同的蛋白质-蛋白质相互作用的模块或不可识别的图案，fbxs。该基因编码的蛋白属于fbxs类，作为肿瘤蛋白p53的转录靶，被认为是参与针对p53诱导特异蛋白的降解。选择性剪接导致多个转录变体。[ RefSeq提供，DEC 2010 ]