Anti-CACNB1/FITC Conjugated抗体
产品名称: Anti-CACNB1/FITC Conjugated抗体
英文名称: Anti-CACNB1/FITC
产品编号: YB--6517R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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Anti-CACNB1/FITC Conjugated抗体
产品编号 | YB-6517R-FITC |
英文名称 | Anti-CACNB1/FITC |
中文名称 | FITC标记的钙通道电压依赖性β1蛋白抗体 |
别 名 | CAB1; CACNLB1; Calcium channel voltage dependent beta 1 subunit; Voltage dependent L type calcium channel beta 1 subunit; CACB1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 信号转导 转录调节因子 通道蛋白 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 66kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CACNB1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by CACNB1 belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Subunit: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with JSRP1. Interacts with RYR1 (By similarity). Subcellular Location: Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Tissue Specificity: Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle. Similarity: Belongs to the calcium channel beta subunit family. Contains 1 SH3 domain. Database links: Entrez Gene: 327703 Cow Entrez Gene: 782 Human Entrez Gene: 12295 Mouse Entrez Gene: 50688 Rat Omim: 114207 Human SwissProt: Q9MZL7 Cow SwissProt: Q02641 Human SwissProt: Q8R3Z5 Mouse SwissProt: P19517 Rabbit SwissProt: P54283 Rat Unigene: 635 Human Unigene: 41252 Mouse Unigene: 9417 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicationS |