HLA-DQA2/HLA-DQA1 polyclonal antibody
产品名称: HLA-DQA2/HLA-DQA1 polyclonal antibody
英文名称: HLA-DQA2/HLA-DQA1 polyclonal antibody
产品编号: PAB19063
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of HLA-DQA2.
- Immunogen:
- A synthetic peptide corresponding to amino acids at C-terminus of human HLA-DQA2.
- Sequence:
- C-QGLRSVGASRH
- Host:
- Goat
- Theoretical MW (kDa):
- 28
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3118
- Protein Accession#:
- NP_064440.1 (Gene ID : 3118);NP_002113.2 (Gene ID : 3117)
- Gene Name:
- HLA-DQA2
- Gene Alias:
- HLA-DXA
- Gene Description:
- major histocompatibility complex, class II, DQ alpha 2
- Gene Ontology:
- Hyperlink
- Other Designations:
- OTTHUMP00000029144
- Entrez GeneID:
- 3117
- Protein Accession#:
- NP_064440.1 (Gene ID : 3118);NP_002113.2 (Gene ID : 3117)
- Gene Name:
- HLA-DQA1
- Gene Alias:
- CD,CELIAC1,DQ-A1,FLJ27088,FLJ27328,GSE,HLA-DQA,MGC149527
- Gene Description:
- major histocompatibility complex, class II, DQ alpha 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq
- Other Designations:
- Gluten-sensitive enteropathy (celiac disease),MHC HLA-DQ alpha,MHC class II HLA-D alpha glycoprotein,MHC class II HLA-DQ-alpha-1,MHC class II antigen,MHC class II surface glycoprotein,OTTHUMP00000029141,OTTHUMP00000176885,OTTHUMP00000178551,OTTHUMP0000017