CDC2 (N-term) Peptide
产品名称： CDC2 (N-term) Peptide
英文名称： CDC2 (N-term) Peptide
产品编号： P0496
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CDC2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDC2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1.
Forester CM, Maddox J, Louis JV, Goris J, Virshup DM.Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19867-72. Epub 2007 Dec 4.
- 2.
- Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed.
Skoufias DA, Indorato RL, Lacroix F, Panopoulos A, Margolis RL.J Cell Biol. 2007 Nov 19;179(4):671-85.
- 3.
- Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS.
Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK.Cell Cycle. 2007 Jul 1;6(13):1594-604. Epub 2007 Apr 20.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of CDC2 polyclonal antibody (Cat # PAB3536) in 293 cell line lysates (35 ug/lane). CDC2 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Entrez GeneID:
- 983
- Protein Accession#:
- NP_001777;P06493
- Gene Name:
- CDC2
- Gene Alias:
- CDC28A,CDK1,DKFZp686L20222,MGC111195
- Gene Description:
- cell division cycle 2, G1 to S and G2 to M
- Omim ID:
- 116940
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019660,cell cycle controller CDC2,cell division control protein 2 homolog,cell division cycle 2 protein,cyclin-dependent kinase 1,p34 protein kinase
- Gene Pathway