FITC标记的胸腺基质淋巴细胞生成素受体抗体
产品名称： FITC标记的胸腺基质淋巴细胞生成素受体抗体
英文名称： Anti-CRLF2/FITC
产品编号： HZ-4652R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CRLF2/FITC Conjugated antibody
FITC标记的胸腺基质淋巴细胞生成素受体抗体
| 英文名称 | Anti-CRLF2/FITC |
| 中文名称 | FITC标记的胸腺基质淋巴细胞生成素受体抗体 |
| 别 名 | CRL 2; CRL2; CRLF 2; Crlf2; CRLF2_MOUSE; CRLF2Y; Cytokine receptor CRL2 precusor; Cytokine receptor like 2; Cytokine receptor like factor 2; Cytokine receptor like factor 2 precursor; Cytokine receptor-like 2; Cytokine receptor-like factor 2; IL XR; IL-XR; ILXR; Thymic stromal derived lymphopoietin receptor; Thymic stromal lymphopoietin protein receptor; Thymic stromal lymphopoietin receptor; TSLP receptor; TSLPR. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CRLF2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. Tissue specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells. Function: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. Subunit: Heterodimer of CRLF2 and IL7R. Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Tissue Specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells. Similarity: Belongs to the type I cytokine receptor family. Type 5 subfamily. Contains 1 fibronectin type-III domain. Database links: Entrez Gene: 64109 Human Entrez Gene: 57914 Mouse Entrez Gene: 171499 Rat Omim: 300357 Human Omim: 400023 Human SwissProt: Q9HC73 Human SwissProt: Q8CII9 Mouse SwissProt: Q8R4S8 Rat Unigene: 287729 Human Unigene: 35771 Mouse Unigene: 177948 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
胸腺基质淋巴生成素受体（TSLP）。用TSLP和IL7R形成功能性复合物，能够通过激活STAT3和STAT5刺激细胞增殖。还激活JAK2（通过相似性）。与造血系统的发育有关。
组织特异性：在心脏、骨骼肌、肾脏和成人和胎儿肝脏中表达。主要在树突和单核细胞中表达。在T细胞中弱表达。