FITC标记的DNA拓普西异构酶Topo IIIα抗体
产品名称： FITC标记的DNA拓普西异构酶Topo IIIα抗体
英文名称： Anti-Topoisomerase III/FITC
产品编号： HZ-7360R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Topoisomerase III/FITC Conjugated antibody
FITC标记的DNA拓普西异构酶Topo IIIα抗体
| 英文名称 | Anti-Topoisomerase III/FITC |
| 中文名称 | FITC标记的DNA拓普西异构酶Topo IIIα抗体 |
| 别 名 | DNA topoisomerase 3 alpha; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; TOP 3; TOP3; TOP3A; TOP3A_HUMAN; topoisomerase (DNA) III alpha; topoisomerase (DNA) III; topoisomerase III alpha; Topo-IIIα. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 112kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Topoisomerase III |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008] Function: Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Tissue Specificity: High expression is found in testis, heart, skeletal muscle and pancreas. Similarity: Belongs to the prokaryotic type I/III topoisomerase family. Contains 1 Toprim domain. Database links: Entrez Gene: 7156 Human Omim: 601243 Human SwissProt: Q13472 Human Unigene: 592115 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
这个基因编码一个DNA拓扑异构酶，一种控制和改变DNA转录过程中的拓扑状态的酶。这种酶催化单链DNA的瞬时断裂和重新连接，从而允许链相互穿过，从而减少超线圈的数量并改变DNA的拓扑结构。这种酶与BLM形成复合物，其作用于体细胞重组的调节。[ RefSeq，JUL 2008 ]